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Arterial Reocclusion in Stroke Patients Treated with Intravenous Tissue Plasminogen Activator Neurol 59:862-867, Alexandrov,A.V. &Grotta,J.C., 2002 See this aricle in Pubmed Article Abstract Early reocclusion occurs in 34% of TPA-treated patients with any initial recanalization, accounting for two-thirds of deteriorations following improvement. Reocclusion occurs more often in patients with earlier and partial recanalization, l eading to neurologic deterioration and higher in-hospital mortality. However, patients with reocclusion have better long-term outcomes than patients without any early recanalization.

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